An image sensor includes a pixel array including pixels, an image data generation circuit configured to generate first image data based on signals of the pixels and output the first image data, and an image data translation circuit configured to generate second image data based on translating the first image data and outputting the second image data to an external host device. The image data generation circuit has a vertical blank interval and a frame interval alternately, is configured to not output the first image data during the vertical blank interval, and is configured to output one frame of the first image data during the frame interval. The image data translation circuit is configured to perform a preparation operation to translate a frame of the first image data into a frame of the second image data in a next frame interval, during the vertical blank interval.