Invention Publication
- Patent Title: GLUCOKINASE (GCK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
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Application No.: US18509583Application Date: 2023-11-15
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Publication No.: US20240287524A1Publication Date: 2024-08-29
- Inventor: Kevin Fitzgerald , David Erbe , Gregory Hinkle
- Applicant: Alnylam Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/713 ; A61K45/06
Abstract:
The invention relates to double stranded ribonucleic acid (dsRNA) compositions targeting a glucokinase (GCK) gene, as well as methods of inhibiting expression of a glucokinase (GCK) gene, and methods of treating subjects having a glycogen storage disease (GSD), e.g., type Ia GSD.
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