发明公开
- 专利标题： BINDING MOLECULES
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申请号： US18405910申请日： 2024-01-05
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公开(公告)号： US20240228617A1公开(公告)日： 2024-07-11
- 发明人: Jakub JAWORSKI , Kate ATKIN , Arnaud TECHINE , Vijaykumar KARUPPIAH , Florence SCHLOSSER , Ana PEREIRA RIBEIRO , Chandramouli CHILLAKURI , Nathaniel LIDDY , Andrew CREESE , Martin EBNER
- 申请人： Immunocore Limited
- 申请人地址： GB Abingdon
- 专利权人： Immunocore Limited
- 当前专利权人： Immunocore Limited
- 当前专利权人地址： GB Abingdon
- 优先权： GB 00227.2 2023.01.06
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61P35/00
摘要：
The present invention relates to binding molecules that comprise T cell receptor (TCR) variable domains and which can bind to a PRAME peptide-HLA complex. In particular, the present invention relates to binding molecules that bind to PYLGQMINL (SEQ ID NO: 1) in complex with HLA-A24. The invention also relates to the use of such molecules for the treatment of malignant diseases.
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