Disclosed are systems and methods for connecting a hydraulic fracturing fluid source to various wells at a given well site. In general, use of disclosed systems and methods provide for repositioning (refocusing) the hydraulic fracturing operation amongst multiple wells may be achieved. In one example, a system to reroute fracturing fluid from a source to various wells at a well site may be provided. The use of adapters and quick clamp connections allow hydraulic fracturing fluid to be rerouted between various wells in a manner to decrease the cost and reduce hazards associated with changing hydraulic fracturing locations. Modular components of the system (and an overall modular design of the system itself) may allow a centralized manifold to be relocated to various locations at one or more well sites.