- 专利标题： CHIMERIC COSTIMULATORY RECEPTORS, CHEMOKINE RECEPTORS, AND THE USE OF SAME IN CELLULAR IMMUNOTHERAPIES
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申请号： US18555513申请日： 2022-04-19
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公开(公告)号： US20240207318A1公开(公告)日： 2024-06-27
- 发明人: Rafael Cubas , Frederick G. Vogt , Yongliang Zhang
- 申请人： Yongliang ZHANG , Iovance Biotherapeutics, Inc.
- 申请人地址： US FL Wesley Chapel
- 专利权人： Yongliang ZHANG,Iovance Biotherapeutics, Inc.
- 当前专利权人： Yongliang ZHANG,Iovance Biotherapeutics, Inc.
- 当前专利权人地址： US FL Wesley Chapel
- 国际申请： PCT/US2022/025420 2022.04.19
- 进入国家日期： 2023-10-14
- 主分类号： A61K35/17
- IPC分类号： A61K35/17 ; A61K38/20 ; A61K39/00 ; A61P35/00 ; C07K16/28 ; C07K16/30 ; C12N5/0783 ; C12N15/86
摘要：
The present invention provides compositions comprising chimeric receptors, including chimeric costimulatory receptors (CCRs), and/or chemokine receptors, methods for preparing CCRs and/or chemokine receptors, and therapeutic populations of tumor infiltrating lymphocytes, marrow infiltrating lymphocytes, and peripheral blood lymphocytes expressing CCRs and/or chemokine receptors with increased therapeutic performance and other advantages for the treatment of cancers, including solid tumor cancers.
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