Invention Publication
- Patent Title: ANGIOPOIETIN-LIKE 3 (ANGPTL3) IRNA COMPOSITIONS AND METHODS OF USE THEREOF
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Application No.: US18337495Application Date: 2023-06-20
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Publication No.: US20240200075A1Publication Date: 2024-06-20
- Inventor: William Querbes , Kevin Fitzgerald , James Butler , Stephanie Williams , Gregory Hinkle , Martin A. Maier
- Applicant: Alnylam Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/713 ; A61K47/54
Abstract:
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.
Information query
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