Provided is a wire connector including a first cover and a second cover that exhibit electrically insulating property. In the assembled state, the first cover and the second cover surround an internal space and define a plurality of ports through which the wire is inserted. Further, the wire connector also includes a seal accommodated in the internal space. In the assembled state, the seal closes the gap between the first cover and the second cover, and closes all ports whether there are wires passing through the ports or not, thus isolates the internal space from the exterior by the sealing of the seal. In this way, in an assembled state of the first cover and the second cover, the wire connector has a good sealing effect. Further provided is an operation method of the wire connector.