A high-speed data cable includes first and second electrical connectors at each end of the cable. A first connector housing is mounted on the first electrical connector, and a second connector housing is mounted on the second electrical connector. The first connector housing includes a first outer periphery and a first mechanical key on the first outer periphery. The first mechanical key engages a first complementary key on a first housing for a first device to define a single orientation by which the first electrical connector plugs into the first device. The second connector housing includes a second outer periphery and a second mechanical key on the second outer periphery. The second mechanical key engages a second complementary key on a second housing for a second device to define a single orientation by which the second electrical connector plugs into the second device.