- 专利标题: ANTIBODY RECRUITMENT MOLECULES AND METHODS OF TREATING CANCER USING SAME
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申请号: US18547714申请日: 2022-02-24
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公开(公告)号: US20240156972A1公开(公告)日: 2024-05-16
- 发明人: Anthony RULLO , Yonghong WAN , Harrison McCann , Benjamin LAKE
- 申请人: McMaster University
- 申请人地址: CA Hamilton
- 专利权人: McMaster University
- 当前专利权人: McMaster University
- 当前专利权人地址: CA ON Hamilton
- 国际申请: PCT/CA2022/050267 2022.02.24
- 进入国家日期: 2023-08-24
- 主分类号: A61K47/64
- IPC分类号: A61K47/64 ; A61K35/763 ; A61K47/54 ; A61K47/60 ; A61P35/00 ; C07K14/005
摘要:
The present disclosure relates generally to the field of cancer immunotherapy. More particularly, the present disclosure provides antibody recruitment molecules, pharmaceutical compositions comprising same and kits comprising same. The present disclosure also provides methods of treating cancer using the antibody recruitment molecules in combination with oncolytic virus therapy, and methods for enhancing the efficacy and/or reducing the toxicity of the oncolytic virus therapy.
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