- 专利标题： ANTI-4-1BB ANTIBODIES AND METHODS OF MAKING AND USING THEREOF
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申请号： US18358834申请日： 2023-07-25
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公开(公告)号： US20240067741A1公开(公告)日： 2024-02-29
- 发明人: Ole OLSEN , Dong XIA , David JELLYMAN , Brian KOVACEVICH , Bill BRADY , Blair RENSHAW , Zeren GAO , Yi ZHU
- 申请人： SYSTIMMUNE, INC. , BAILI-BIO (CHENGDU) PHARMACEUTICAL CO., LTD.
- 申请人地址： US WA Redmond
- 专利权人： SYSTIMMUNE, INC.,BAILI-BIO (CHENGDU) PHARMACEUTICAL CO., LTD.
- 当前专利权人： SYSTIMMUNE, INC.,BAILI-BIO (CHENGDU) PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： US WA Redmond
- 分案原申请号： US16615119 2019.11.19
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395 ; A61K45/06
摘要：
The application provides anti-4-1BB monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
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