A conception of locating and completely cleaning indoor air pollution is provided. A plurality of physical or chemical first devices are disposed to determine characteristics, concentrations and locations of air pollution. A fan, a physical second device or a chemical second device is selected and enabled in accordance with the position closest to the location of the air pollution to generate an airflow. Various mathematical operations and artificial intelligence operations are implemented to improve efficiency of locating the air pollution, draining the air pollution and completely cleaning the air pollution. A wired and wireless network is utilized to optimize efficacy of the physical second device or the chemical second device. The mathematical operations are utilized through the wired and wireless network to maximize effects of the physical second device and the chemical second device for completely cleaning the air pollution.