A multi-channel endoscope can include a control section and an insertion end. The endoscope can include a user control mechanism. The control section can include at least one working channel and a channel within the control section. The working channel can accommodate at least one medical instrument which can fracture a target object into fragments. A catheter, such as a fluidic catheter, can extend from and retract to an originating proximal position at the insertion end of the endoscope. A vacuum pressure source or an irrigation source can be coupled to a proximal end of the channel. The user control mechanism can control the position of the catheter with respect to the endoscope and can be used to operate the vacuum pressure source or irrigation source.