- 专利标题: AN IMPLANTABLE MEDICAL DEVICE
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申请号: US17629883申请日: 2020-06-29
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公开(公告)号: US20230094196A1公开(公告)日: 2023-03-30
- 发明人: Ellen ROCHE , Eimear DOLAN , Garry DUFFY , Sandra ROTHENBUCHER , William WHYTE , Claudia VARELA , Scott ROBINSON , Keegan MENDEZ
- 申请人: NATIONAL UNIVERSITY OF IRELAND, GALWAY , MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 申请人地址: IE Galway; US MA Cambridge
- 专利权人: NATIONAL UNIVERSITY OF IRELAND, GALWAY,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人: NATIONAL UNIVERSITY OF IRELAND, GALWAY,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人地址: IE Galway; US MA Cambridge
- 优先权: EP19187842.0 20190723
- 国际申请: PCT/EP2020/068316 WO 20200629
- 主分类号: A61M5/142
- IPC分类号: A61M5/142 ; A61M5/145
摘要:
An implantable medical device having a soft tissue interfacing surface comprises at least one soft actuatable capsule having a soft tissue interfacing deflectable membrane configured for cyclical deflection upon actuation of the capsule to modulate the biomechanics of the soft tissue interface during use. The actuatable capsule may comprise an actuation chamber containing a first fluid, a therapeutic chamber containing a second fluid, a deflectable membrane separating the actuation chamber and therapeutic chamber, and an actuation conduit in fluidic communication with the actuation chamber for pneumatic actuation of the actuation chamber. The therapeutic chamber comprises the soft tissue interfacing deflectable membrane which is configured to cyclically deflect during actuation of the capsule and modulate the biomechanics of the soft tissue interface by altering one or more of strain, fluid flow and cellular activity in peri-implant tissue at the soft tissue interface. Methods of reducing fibrotic encapsulation of an implantable medical device are also described.
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