- 专利标题： VECTORIZED FACTOR XII ANTIBODIES AND ADMINISTRATION THEREOF
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申请号： US18034334申请日： 2021-10-29
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公开(公告)号： US20230390418A1公开(公告)日： 2023-12-07
- 发明人: Joseph Bruder , Ye Liu
- 申请人： REGENXBIO INC.
- 申请人地址： US MD Rockville
- 专利权人： REGENXBIO INC.
- 当前专利权人： REGENXBIO INC.
- 当前专利权人地址： US MD Rockville
- 国际申请： PCT/US21/57319 2021.10.29
- 进入国家日期： 2023-04-27
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C12N15/86 ; C07K16/36 ; A61P7/10
摘要：
Compositions and methods are described for the delivery of a fully human post-translationally modified therapeutic monoclonal antibody that binds to factor XII to a human subject diagnosed with a disease or condition indicated for treatment with an anti-factor XII antibody. Such diseases include hereditary angioedema, as well as thrombosis and hypercoagulation.
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