The present invention is a process to produce Z-Chitosan to provide consistent and long-lasting antimicrobial, antiviral, antibacterial, antifungal, anti-spore, and anti-odor characteristics, the process comprises steps of preparing a liquid active agent comprising 50 ppm to 5,000 ppm aqueous solution of each of a Chitosan group, a herbal extract group, and a catalyst group using an emulsion crosslinking method for 24 to 144 hours at normal room conditions; preparing a powder form of the active agent by drying the liquid active agent; encapsulating the powder form of the active agent within a plastic, a polymer, a fabric to make a masterbatch of the product, and finally blending 1 to 10 percent of the masterbatch with a batch of plastic, polymer, or fabric to make an antimicrobial product, whereby the product shows antimicrobial and self-sanitizing efficacy for contact time between 2 hours to 24 hours and maintains its antimicrobial efficacy in the scale of years in different environment conditions.