- 专利标题： 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS
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申请号： US17984242申请日： 2022-11-10
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公开(公告)号： US20230331729A1公开(公告)日： 2023-10-19
- 发明人: Tjeerd A. Barf , Christiaan Gerardus Johannes Maria Jans , Adrianus Petrus Antonius de Man , Arthur A. Oubrie , Hans C.A. Raaijmakers , Johannes Bernardus Maria Rewinkel , Jan Gerard Sterrenburg , Jacobus C.H.M. Wijkmans
- 申请人： Merck Sharp & Dohme B.V.
- 申请人地址： NL Haarlem
- 专利权人： Merck Sharp & Dohme B.V.
- 当前专利权人： Merck Sharp & Dohme B.V.
- 当前专利权人地址： NL Haarlem
- 优先权： EP 174578.2 2011.07.19
- 分案原申请号： US14233418 2014.01.17
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D519/00 ; A61K31/4985 ; A61K31/501 ; A61K31/506 ; A61K31/55 ; A61K31/5377
摘要：
The present invention relates to 6-5 membered fused pyridine ring compounds according to Formula (I)
or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to Formula (I) in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to Formula (I) in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
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