发明公开
- 专利标题： IMMUNOMODULATORY FUSION PROTEIN-METAL HYDROXIDE COMPLEXES AND METHODS THEREOF
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申请号： US18172905申请日： 2023-02-22
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公开(公告)号： US20230302128A1公开(公告)日： 2023-09-28
- 发明人: Darrell J. IRVINE , Karl Dane Wittrup , Tyson Moyer , Yash Agarwal
- 申请人： Massachusetts Institute of Technology
- 申请人地址： US MA Cambridge
- 专利权人： Massachusetts Institute of Technology
- 当前专利权人： Massachusetts Institute of Technology
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P35/00 ; A61K33/08 ; A61K38/19 ; A61K38/20 ; C07K14/52 ; C07K14/525 ; C07K14/54 ; C07K16/28
摘要：
The present disclosure provides immunomodulatory fusion proteins-metal hydroxide complexes comprising an immunomodulatory domain adsorbed to a metal hydroxide via ligand exchange. The disclosure also features compositions and methods of using the same, for example, to treat cancer.
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