- 专利标题： METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS
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申请号： US18162236申请日： 2023-01-31
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公开(公告)号： US20230295296A1公开(公告)日： 2023-09-21
- 发明人: Felipe Bedoya , Saba Ghassemi , Carl H. June , Bruce L. Levine , Jan J. Melenhorst , Michael C. Milone , Daniel J. Powell, Jr. , Zoe Zheng
- 申请人： Novartis AG , The Trustees of the University of Pennsylvania
- 申请人地址： CH PA Basel
- 专利权人： Novartis AG,The Trustees of the University of Pennsylvania
- 当前专利权人： Novartis AG,The Trustees of the University of Pennsylvania
- 当前专利权人地址： CH PA Basel
- 分案原申请号： US16291651 2019.03.04
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C12N9/12 ; C07K14/705 ; C07K14/725 ; C12N5/0783 ; A61K35/17 ; C12N5/00
摘要：
The invention provides methods of making immune effector cells (e.g., T cells, NK cells) that can be engineered to express a chimeric antigen receptor (CAR), and compositions and reaction mixtures comprising the same.
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