- 专利标题: METHODS OF REVERSING CACHEXIA AND PROLONGING SURVIVAL COMPRISING ADMINISTERING A GDF15 MODULATOR AND AN ANTI-CANCER AGENT
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申请号: US17939634申请日: 2022-09-07
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公开(公告)号: US20230295285A1公开(公告)日: 2023-09-21
- 发明人: Jeno Gyuris , Lorena Lerner , Jie Lin
- 申请人: AVEO Pharmaceuticals, Inc.
- 申请人地址: US MA Boston
- 专利权人: AVEO Pharmaceuticals, Inc.
- 当前专利权人: AVEO Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Boston
- 主分类号: C07K16/22
- IPC分类号: C07K16/22 ; A61K31/555 ; A61K39/395 ; A61K31/704 ; A61K31/7068 ; A61K45/06 ; A61K33/243
摘要:
Methods are provided for improved treatment of subjects with cancer anorexia-cachexia syndrome, comprising treatment with a combination of at least one anti-cancer agent and at least one GDF15 modulator. Methods are further provided for improved treatment of subjects with anti-cancer agents which induce cachexia, comprising further treating the subject with at least one GDF15 modulator.
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