发明公开
- 专利标题： Tetrahydrobenzoazepinones and Related Analogs for Inhibiting YAP/TAZ-TEAD
-
申请号： US18145902申请日： 2022-12-23
-
公开(公告)号： US20230278962A1公开(公告)日： 2023-09-07
- 发明人: Bart VANDERHOYDONCK , Arnaud MARCHAND , Aurélie CANDI , Matthias VERSELE
- 申请人： THE KATHOLIEKE UNIVERSITEIT LEUVEN , SpringWorks Therapeutics, Inc. , VIB vzw
- 申请人地址： BE CT Vlaams-Brabant Leuven
- 专利权人： THE KATHOLIEKE UNIVERSITEIT LEUVEN,SpringWorks Therapeutics, Inc.,VIB vzw
- 当前专利权人： THE KATHOLIEKE UNIVERSITEIT LEUVEN,SpringWorks Therapeutics, Inc.,VIB vzw
- 当前专利权人地址： BE CT Vlaams-Brabant Leuven
- 主分类号： C07D223/16
- IPC分类号： C07D223/16 ; C07D215/227 ; C07D471/04 ; A61P35/00 ; A61K45/06 ; A61K31/55 ; A61K31/4704 ; A61K31/4375
摘要：
The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.
信息查询
