- 专利标题： PLATINUM COMPOUNDS THAT INHIBIT CONSTITUTIVE STAT3 SIGNALING AND INDUCE CELL CYCLE ARREST AND APOPTOSIS OF MALIGNANT CELLS
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申请号： US18162375申请日： 2023-01-31
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公开(公告)号： US20230201191A1公开(公告)日： 2023-06-29
- 发明人: SAID M. SEBTI , NICHOLAS J. LAWRENCE , JAMES TURKSON
- 申请人： H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. , UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
- 申请人地址： US FL TAMPA
- 专利权人： H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.,UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
- 当前专利权人： H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.,UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
- 当前专利权人地址： US FL TAMPA
- 分案原申请号： US14354400 2014.04.25
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; A61K33/243 ; A61K33/24 ; C07D295/088 ; G01N33/50
摘要：
The subject invention concerns a compound and compositions having activity as an inhibitor of Stat3 protein and methods of using the compound and compositions. In one embodiment, a compound of the invention has the structure shown in formula I, formula II, or formula III. The subject invention also concerns methods of using the compounds and compositions of the invention.
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