Invention Publication
- Patent Title: ARGININE METHYLTRANSFERASE 5 (PRMT5) DEGRADERS AND USES THEREOF
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Application No.: US17917075Application Date: 2021-04-05
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Publication No.: US20230149551A1Publication Date: 2023-05-18
- Inventor: Jun Qi , Lei Wu , Paul M. Park , Logan H. Sigua
- Applicant: DANA-FARBER CANCER INSTITUTE, INC.
- Applicant Address: US MA Boston
- Assignee: DANA-FARBER CANCER INSTITUTE, INC.
- Current Assignee: DANA-FARBER CANCER INSTITUTE, INC.
- Current Assignee Address: US MA Boston
- International Application: PCT/US2021/025726 2021.04.05
- Date entered country: 2022-10-05
- Main IPC: A61K47/55
- IPC: A61K47/55 ; A61P35/02 ; A61P35/00 ; A61P11/00
Abstract:
Disclosed are to bifunctional compounds that target PRMT5 for degradation, compositions, and methods for treating diseases or conditions mediated by aberrant arginine methyltransferase 5 (PRMT5) activity.
Information query
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