Provided are a reference signal resource configuration method and apparatus, a device, and a storage medium. The method includes: configuring a plurality of frequency domain units as a frequency domain unit set, where the frequency domain units are frequency domain resources of a preset frequency segment; configuring a reference signal resource pool corresponding to the frequency domain units, where the reference signal resource pool includes a plurality of reference signal resources, and at least part of the reference signal resources have an association relationship established according to a preset rule or have an association relationship established according to an indication of an association relationship among the frequency domain units; and configuring a preset resource attribute for multiple reference signal resources having an association relationship. The accuracy of estimating a channel feature can be improved by using the reference signal resources for estimating the channel feature.