Invention Application
- Patent Title: SUBSTITUTED N-HETEROCYCLIC CARBOXAMIDES AS ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS
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Application No.: US17760873Application Date: 2020-09-17
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Publication No.: US20220402901A1Publication Date: 2022-12-22
- Inventor: Renato T. Skerlj , Rita Scarpelli , Vincenzo Cilibrasi , Samantha Caputo
- Applicant: Bial - R&D Investments, S.A. , Fondazione Istituto Italiano di Tecnologia
- Applicant Address: PT Coronado (S.Romão e. S.Mamede); IT Genova
- Assignee: Bial - R&D Investments, S.A.,Fondazione Istituto Italiano di Tecnologia
- Current Assignee: Bial - R&D Investments, S.A.,Fondazione Istituto Italiano di Tecnologia
- Current Assignee Address: PT Coronado (S.Romão e. S.Mamede); IT Genova
- International Application: PCT/US2020/051303 WO 20200917
- Main IPC: C07D413/04
- IPC: C07D413/04 ; C07D451/02 ; C07D491/107 ; C07D487/04 ; C07D471/10

Abstract:
The invention provides substituted N-heterocyclic carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat a medical disorder, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.
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