- 专利标题： CO-ADMINISTRATION OF SEASONAL INFLUENZA VACCINE AND AN ADENOVIRUS BASED RESPIRATORY SYNCYTIAL VIRUS VACCINE
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申请号： US17595255申请日： 2020-05-14
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公开(公告)号： US20220273787A1公开(公告)日： 2022-09-01
- 发明人: Benoit Christophe Stephan CALLENDRET , Jerald C. SADOFF , Els DE PAEPE
- 申请人： Janssen Vaccines & Prevention B.V.
- 申请人地址： NL Leiden
- 专利权人： Janssen Vaccines & Prevention B.V.
- 当前专利权人： Janssen Vaccines & Prevention B.V.
- 当前专利权人地址： NL Leiden
- 国际申请： PCT/EP2020/063406 WO 20200514
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; A61P31/14 ; A61P31/16 ; C12N7/00 ; C12N15/86 ; A61K39/145
摘要：
Methods of inducing a protective immune response against respiratory syncytial virus (RSV) and against influenza virus, without inducing a severe adverse event in human subjects are described. The methods include administering to the subjects an effective amount of an adenoviral vector encoding a recombinant RSV F polypeptide that is stabilized in a pre-fusion conformation, along with an effective amount of an influenza vaccine.
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