- 专利标题： USE OF SMALL MOLECULE INHIBITORS TO KLF10 FOR MODULATION OF T REGULATORY CELLS AND CANCER IMMUNOTHERAPY
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申请号： US17587304申请日： 2022-01-28
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公开(公告)号： US20220185801A1公开(公告)日： 2022-06-16
- 发明人: Mark FEINBERG , Santosh A. KHEDKAR
- 申请人： The Brigham and Women's Hospital, Inc. , Beth Israel Deaconess Medical Center, Inc.
- 申请人地址： US MA Boston; US MA Boston
- 专利权人： The Brigham and Women's Hospital, Inc.,Beth Israel Deaconess Medical Center, Inc.
- 当前专利权人： The Brigham and Women's Hospital, Inc.,Beth Israel Deaconess Medical Center, Inc.
- 当前专利权人地址： US MA Boston; US MA Boston
- 主分类号： C07D409/12
- IPC分类号： C07D409/12 ; C07D239/38 ; C07D311/62 ; C07D239/52 ; C07D207/44 ; C07C251/86 ; C07C49/84 ; C07C39/15 ; C07C205/45 ; C07C217/48
摘要：
The invention relates to compositions and methods for inhibiting Krüppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.
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