Invention Application
- Patent Title: Modulating Human Cas9-Specific Host Immune Response
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Application No.: US17546810Application Date: 2021-12-09
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Publication No.: US20220162574A1Publication Date: 2022-05-26
- Inventor: Samira Kiani , Radwa Ewaisha , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mohammad R Ebrahimkhani
- Applicant: Arizona Board of Regents on behalf of Arizona State University
- Applicant Address: US AZ Scottsdale
- Assignee: Arizona Board of Regents on behalf of Arizona State University
- Current Assignee: Arizona Board of Regents on behalf of Arizona State University
- Current Assignee Address: US AZ Scottsdale
- Main IPC: C12N9/22
- IPC: C12N9/22 ; G01N33/573

Abstract:
Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
Public/Granted literature
- US12084691B2 Modulating human Cas9-specific host immune response Public/Granted day:2024-09-10
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