![TETRAHYDRO-1H-CYCLOPENTA[CD]INDENE DERIVATIVES AS HYPOXIA INDUCIBLE FACTOR-2(ALPHA) INHIBITORS](/docs/US/2022-05-26/US20220162158A1/abs.jpg.600x600.jpg)
- 专利标题： TETRAHYDRO-1H-CYCLOPENTA[CD]INDENE DERIVATIVES AS HYPOXIA INDUCIBLE FACTOR-2(ALPHA) INHIBITORS
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申请号： US17670423申请日： 2022-02-11
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公开(公告)号： US20220162158A1公开(公告)日： 2022-05-26
- 发明人: Jiping FU , Yan LOU , Yigang HE
- 申请人： NIKANG THERAPEUTICS, INC.
- 申请人地址： US DE Wilmington
- 专利权人： NIKANG THERAPEUTICS, INC.
- 当前专利权人： NIKANG THERAPEUTICS, INC.
- 当前专利权人地址： US DE Wilmington
- 主分类号： C07C255/54
- IPC分类号： C07C255/54 ; A61P35/00 ; C07C313/06 ; C07D213/63 ; C07D233/60
![TETRAHYDRO-1H-CYCLOPENTA[CD]INDENE DERIVATIVES AS HYPOXIA INDUCIBLE FACTOR-2(ALPHA) INHIBITORS](/abs-image/US/2022/05/26/US20220162158A1/abs.jpg.150x150.jpg)
摘要：
The present disclosure provides certain tetrahydro-1H-cyclopenta[cd]indene compounds that are Hypoxia Inducible Factor 2α (HIF-2α) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of HIF-2α. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
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