An intellectual host switching system is disclosed, which is installed in multi host devices, and comprises a host switching setting unit and a host switching executing unit. The host switching setting unit provides a plurality of color regions on a display screen of the host device, and the color regions are corresponding to multi host devices by a setting operation of host switching. In case of a pointer being moved to be in a color region as well as a motion distance of the pointer being smaller than a reference motion distance, the host switching executing unit executes a host switching operation after receiving a host switching command that is transmitted from a wireless inputting device, thereby making the wireless inputting device wirelessly connected with one host device be switched to be wirelessly connected with another one host device, without completing any Bluetooth pairing procedure.