- 专利标题： DIMERS AND USE THEREOF
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申请号： US17229392申请日： 2021-04-13
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公开(公告)号： US20210246210A1公开(公告)日： 2021-08-12
- 发明人: Ting Xu , Kangping Guo , Dong Yang , Pilin Wang , Yuhao Jin , Xiaoxiao Wang
- 申请人： JIANGSU ALPHAMAB BIOPHARMACEUTICALS CO., LTD.
- 申请人地址： CN Suzhou
- 专利权人： JIANGSU ALPHAMAB BIOPHARMACEUTICALS CO., LTD.
- 当前专利权人： JIANGSU ALPHAMAB BIOPHARMACEUTICALS CO., LTD.
- 当前专利权人地址： CN Suzhou
- 优先权： CNPCT/CN2018/090012 20180605,CNPCT/CN2019/086821 20190514
- 主分类号： C07K16/28
- IPC分类号： C07K16/28
摘要：
The present disclosure provides a dimer formed by two polypeptide chains, with each of the two polypeptide chains comprising an antibody Fc subunit, wherein the dimer comprises two or more immunoglobulin single variable domains (ISVDs), at least one of the ISVDs is specific for PD-L1, and at least one of the ISVDs is specific for CTLA4.
公开/授权文献
- US11634492B2 Dimers and use thereof 公开/授权日：2023-04-25
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