- 专利标题： METHOD FOR PRODUCING HUMAN INDUCED PLURIPOTENT STEM CELLS CONTAINING EXOGENOUS CHROMOSOME
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申请号： US17257182申请日： 2019-10-10
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公开(公告)号： US20210123027A1公开(公告)日： 2021-04-29
- 发明人: Yasuhiro KAZUKI , Narumi UNO , Mitsuo OSHIMURA
- 申请人： NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY , Trans Chromosomics, Inc.
- 申请人地址： JP Tottori-shi, Tottori; JP Yonago-shi, Tottori
- 专利权人： NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY,Trans Chromosomics, Inc.
- 当前专利权人： NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY,Trans Chromosomics, Inc.
- 当前专利权人地址： JP Tottori-shi, Tottori; JP Yonago-shi, Tottori
- 优先权： JP2018-191894 20181010
- 国际申请： PCT/JP2019/040090 WO 20191010
- 主分类号： C12N5/074
- IPC分类号： C12N5/074 ; C12N5/10
摘要：
The present application provides: a method for producing human induced pluripotent stem (iPS) cells comprising an exogenous chromosome having a DNA of interest using the MMCT method; and a method for expressing the exogenous gene in the human iPS cells prepared by the method for producing human iPS cells, or in undifferentiated or differentiated cells derived from the human iPS cells induced to differentiate from the human iPS cells.
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