Invention Application
- Patent Title: COMPOUNDS HAVING S1P5 RECEPTOR AGONISTIC ACTIVITY
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Application No.: US16970865Application Date: 2019-02-21
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Publication No.: US20210087141A1Publication Date: 2021-03-25
- Inventor: Toshihide WATANABE , Kensuke KUSUMI , Satomi IMAIDE , Toshimitsu ENDO , Takaki KOMIYA , Naomi TSUBURAYA
- Applicant: ONO PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Osaka
- Assignee: ONO PHARMACEUTICAL CO., LTD.
- Current Assignee: ONO PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Osaka
- Priority: JP2018-029549 20180222
- International Application: PCT/JP2019/006637 WO 20190221
- Main IPC: C07D205/04
- IPC: C07D205/04 ; C07C49/577 ; C07C49/252

Abstract:
A compound represented by the general formula (V) wherein all the symbols are as defined in the specification, has an improved balance of the agonist activity against the S1P5 receptor relative to the S1P1 receptor, and can thus serve as a therapeutic agent for S1P5-mediated diseases such as schizophrenia and Binswanger's disease and other neurodegenerative diseases.
Public/Granted literature
- US11198672B2 Compounds having S1P5 receptor agonistic activity Public/Granted day:2021-12-14
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