- 专利标题： MEDITOPE-ENABLED T CELLS
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申请号： US16958614申请日： 2018-12-31
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公开(公告)号： US20210061879A1公开(公告)日： 2021-03-04
- 发明人: John C. WILLIAMS , Christine BROWN , Kurt JENKINS , Yi-Chiu KUO , Cheng-Fu KUO
- 申请人： CITY OF HOPE
- 申请人地址： US CA Duarte
- 专利权人： CITY OF HOPE
- 当前专利权人： CITY OF HOPE
- 当前专利权人地址： US CA Duarte
- 国际申请： PCT/US18/68235 WO 20181231
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C07K14/725 ; C07K16/28 ; C12N15/86
摘要：
Provided herein are compositions which exhibit novel therapeutic capabilities and allow to reduce the off-target effect of therapeutic antibodies. The compositions include recombinant proteins that if expressed by a T cell can efficiently recruit therapeutic antibodies to their site of action.
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