According to one embodiment, a medical information processing system includes processing circuitry. The processing circuitry acquires an ultrasound image of a subject. The processing circuitry acquires a first modality image of the subject, the first modality image differing from the ultrasound image. The processing circuitry acquires an imaging position for the ultrasound image. The processing circuitry generates diagnosis support information for the subject based on the ultrasound image, the imaging position for the ultrasound image, and the first modality image.