Invention Application
- Patent Title: METHODS FOR USING CD137 LIGAND AS A BIOMARKER FOR TREATMENT WITH ANTI-CD137 ANTIBODY
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Application No.: US16768500Application Date: 2018-11-30
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Publication No.: US20200377608A1Publication Date: 2020-12-03
- Inventor: Peter Peizhi LUO , Guizhong LIU , Fangyong DU
- Applicant: Peter Peizhi LUO , Adagene Inc.
- Applicant Address: KY Grand Cayman
- Assignee: Adagene Inc.
- Current Assignee: Adagene Inc.
- Current Assignee Address: KY Grand Cayman
- Priority: CNPCT/CN2017/114247 20171201
- International Application: PCT/CN2018/118631 WO 20181130
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P35/00
Abstract:
Provided herein are methods relating to the use of CD137 Ligand (CD137L) expression; methods relating to the use of CD137L expression as a biomarker; and methods for predicting, assessing, and/or aiding in assessment of responsiveness of a subject in need thereof to treatment with particular anti-cancer therapies (e.g., an anti-CD137 antibody, a checkpoint blockade immunotherapy).
Information query
