Invention Application
- Patent Title: IMMUNOTHERAPEUTIC COMPOSITIONS FOR TREATMENT OF GLIOBLASTOMA MULTIFORME
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Application No.: US16888398Application Date: 2020-05-29
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Publication No.: US20200376113A1Publication Date: 2020-12-03
- Inventor: David Evander Anderson
- Applicant: Variation Biotechnologies Inc.
- Main IPC: A61K39/245
- IPC: A61K39/245 ; C07K14/005 ; A61P35/00 ; C12N7/00
Abstract:
The present disclosure provides compositions and methods useful for treating Glioblastoma Multiforme (GBM), e.g., compositions comprising virus-like particles (VLPs) comprising Moloney Murine leukemia virus (MMLV) core proteins and the human cytomegalovirus epitopes, gB and pp65, formulated with GM-CSF, which, at dose of at least 10 μg gB/pp65Gag, reverse dysregulation of anti-HCMV immunity in GBM patients.
Information query
