COMPOSITIONS AND METHODS COMPRISING HISTIDYL-TRNA SYNTHETASE SPLICE VARIANTS HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES

Invention Application

US20200231704A1 COMPOSITIONS AND METHODS COMPRISING HISTIDYL-TRNA SYNTHETASE SPLICE VARIANTS HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES 审中-公开

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Patent Title: COMPOSITIONS AND METHODS COMPRISING HISTIDYL-TRNA SYNTHETASE SPLICE VARIANTS HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES
Application No.: US16842195

Application Date: 2020-04-07
Publication No.: US20200231704A1

Publication Date: 2020-07-23
Inventor: Jie ZHOU , Ching-Fun LAU , Zhiwen XU , Wing-Sze LO , Kristi Helen PIEHL , Leslie Ann GREENE
Applicant: aTyr Pharma, Inc. , Pangu BioPharma Limited
Main IPC: C07K16/40
IPC: C07K16/40 ; C12Q1/6876 ; C12N15/113 ; C12Q1/6886 ; C12N9/00 ; G01N33/573

COMPOSITIONS AND METHODS COMPRISING HISTIDYL-TRNA SYNTHETASE SPLICE VARIANTS HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES

Abstract:

Isolated histidyl-tRNA synthetase splice variant polynucleotides and polypeptides having non-canonical biological activities are provided, as well as compositions and methods related thereto.

Public/Granted literature

US11078299B2 Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities Public/Granted day:2021-08-03

Information query

Global Dossier Espacenet

IPC分类:

C	化学；冶金
C07	有机化学
C07K	肽（含有β-内酰胺的肽入C07D；在分子中除了形成本身的肽环外不含有任何其他的肽键的环状二肽，如哌嗪-2,5-二酮入C07D；环肽型麦角生物碱入C07D519/02；单细胞蛋白质、酶入C12N；获得肽的基因工程方法入C12N15/00）
C07K16/00	免疫球蛋白，例如，单克隆或多克隆抗体
C07K16/40	.抗酶