- 专利标题： QUINONE-CONTAINING CONJUGATES
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申请号： US16523384申请日： 2019-07-26
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公开(公告)号： US20200030456A1公开(公告)日： 2020-01-30
- 发明人: Wenhui Zhou , Hui Wang , James J. Cali , Sarah Duellman , Jolanta Vidugiriene , Natasha Karassina
- 申请人： PROMEGA CORPORATION
- 主分类号： A61K47/68
- IPC分类号： A61K47/68 ; C07K16/30 ; A61K31/122
摘要：
Conjugates comprise a drug or probe, a cell binding agent, and a quinone-containing linker. The quinone-containing linker may be reduced intracellularly to trigger release of the drug or probe. These conjugates may selectively deliver a drug or probe to a site of action of interest for local release of the active drug or probe.
公开/授权文献
- US11857638B2 Quinone-containing conjugates 公开/授权日：2024-01-02
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