An optical system includes an array of optical elements configured to receive a primary laser beam and generate a plurality of sub-beams. The array of optical elements includes a plurality of optical elements that are configured to simultaneously focus the plurality of sub-beams to a plurality of focal regions in a target tissue. A pitch of the array of optical elements ranges from about 1 mm to about 3 mm. A numerical aperture of one or more optical elements of the plurality of optical element ranges from about 0.3 to about 1. A first sub-beam of the plurality sub-beams is configured to generate plasma in a first focal region of the plurality of focal regions.