A footwear cleaning device comprises a housing, a brushing system disposed in an interior of the housing, and a spraying system disposed in the interior of the housing. The housing has a lid with an encasement portion. The encasement portion is formed of a semi-rigid, waterproof material and has an opening adapted to receive a footwear and expose only a sole of the footwear to the interior of the housing. The brushing system includes a brush and a driving device driving the brush to have a translational movement with respect to the housing and the sole of the footwear. The spraying system is adapted to spray a cleaning solution on the brush.