- 专利标题： COMPOUNDS USEFUL FOR ALTERING THE LEVELS OF BILE ACIDS FOR THE TREATMENT OF DIABETES AND CARDIOMETABOLC DISEASE
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申请号： US16324596申请日： 2017-08-10
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公开(公告)号： US20190218223A1公开(公告)日： 2019-07-18
- 发明人: Jared N. Cumming , Kevin D. Dykstra , Alan Hruza , Derun Li , Hong Liu , Haiqun Tang , Brandon M. Taoka , Andreas Verras , Shawn P. Walsh , Wen-Lian Wu
- 申请人： Jared N. CUMMING , Kevin D. DYKSTRA , Alan HRUZA , Derun LI , Hong LIU , Haiqun TANG , Brandon M. TAOKA , Andreas VERRAS , Shawn P. WALSH , Wen-Lian WU , Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 国际申请： PCT/US2017/046186 WO 20170810
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D519/00 ; C07D471/04 ; C07D498/04 ; C07D513/04 ; A61P3/10
摘要：
Described herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.
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