Invention Application
- Patent Title: SYSTEMS AND METHODS FOR REAL-TIME, TRANSCRANIAL MONITORING OF BLOOD-BRAIN BARRIER OPENING
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Application No.: US16042294Application Date: 2018-07-23
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Publication No.: US20190192112A1Publication Date: 2019-06-27
- Inventor: Elisa E. Konofagou , Tobias Teichert , Vincent P. Ferrera , Fabrice Marquet , Yao-Sheng Tung , Shih-Ying Wu
- Applicant: The Trustees of Columbia University in the City of New York
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Main IPC: A61B8/08
- IPC: A61B8/08 ; A61N7/02 ; A61B8/00

Abstract:
Systems and techniques for real-time, transcranial monitoring of safe blood-brain barrier opening include determining an approach angle for targeted blood-brain barrier opening proximate a predetermined region in a brain of a patient, and positioning an ultrasound transducer to generate a focused ultrasound signal at the determined approach angle to the predetermined region in the brain.
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