Machine learning is used to control environmental systems for a building or other man-made structure. In one approach, environmental data is collected by sensors for an environment within the man-made structure. The environmental data is used as input to a machine learning model that predicts at least one attribute affecting control of the environment within the man-made structure. For example, the machine learning model might predict load on the environmental system, resource consumption by the environmental system, or cost of operating the environmental system. The environmental system for the man-made structure is controlled based on the predicted attribute.