- 专利标题： PREPARATION OF MULTI-HAPTEN MUTANT G6PDH CONJUGATES AND THEIR USE FOR DETECTION OF MULTIPLE ANALYTES
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申请号： US16179311申请日： 2018-11-02
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公开(公告)号： US20190055538A1公开(公告)日： 2019-02-21
- 发明人: Yi Feng Zheng , Yali Yang , Linda Hudson , Nihmat Morjana
- 申请人： Siemens Healthcare Diagnostics Inc.
- 申请人地址： US NY Tarrytown
- 专利权人： Siemens Healthcare Diagnostics Inc.
- 当前专利权人： Siemens Healthcare Diagnostics Inc.
- 当前专利权人地址： US NY Tarrytown
- 主分类号： C12N9/96
- IPC分类号： C12N9/96 ; G01N33/58 ; C12N9/04 ; G01N33/535
摘要：
The present invention relates to multi-hapten mutant G6PDH conjugates, methods of their preparation and their use for detection of multiple analytes. The compositions of the invention comprise different types of haptens (molecules) require to be immobilized into the G6PDH to make one multi-hapten-G6PDH conjugate. Both thiol and amine functional groups on G6PDH are utilized for immobilization of different haptens.
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