Invention Application
- Patent Title: COMPOSITIONS AND METHODS FOR INDUCING CONFORMATIONAL CHANGES IN CEREBLON AND OTHER E3 UBIQUITIN LIGASES
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Application No.: US16049708Application Date: 2018-07-30
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Publication No.: US20190030019A1Publication Date: 2019-01-31
- Inventor: Philip Chamberlain , Brian E. Cathers , Antonia Lopez-Girona
- Applicant: Celgene Corporation
- Main IPC: A61K31/454
- IPC: A61K31/454 ; C12Q1/37 ; A61K31/517 ; G06F19/16
Abstract:
Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.
Public/Granted literature
- US10668057B2 Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases Public/Granted day:2020-06-02
Information query
IPC分类:
