发明申请
- 专利标题： Compositions and Methods for Treating Pathological Calcification and Ossification
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申请号： US16033948申请日： 2018-07-12
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公开(公告)号： US20180318401A1公开(公告)日： 2018-11-08
- 发明人: Demetrios Braddock , Ronald Albright
- 申请人： YALE UNIVERSITY
- 主分类号： A61K38/46
- IPC分类号： A61K38/46 ; C12N9/14 ; C12N9/16
摘要：
The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
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