Invention Application
- Patent Title: COMPOSITIONS FOR TREATING AND/OR PREVENTING CELL OR TISSUE NECROSIS SPECIFICALLY TARGETING CATHEPSIN C AND/OR CELA1 AND/OR CELA3A AND/OR STRUCTURALLY RELATED ENZYMES THERETO
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Application No.: US15564836Application Date: 2016-04-07
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Publication No.: US20180312477A1Publication Date: 2018-11-01
- Inventor: Ilana Nathan , Boris Khalfin
- Applicant: ELA PHARMA LTD
- International Application: PCT/IL2016/050371 WO 20160407
- Main IPC: C07D265/22
- IPC: C07D265/22 ; A61K45/06 ; C12N5/077 ; A61P25/00 ; A61K31/426 ; A61K31/536 ; C07D277/42 ; C07D233/48 ; A61K31/4178 ; C07C233/24 ; A61K31/167 ; C07D275/06 ; A61K31/428 ; A61K31/454
Abstract:
Inhibitor compounds and agents of Cathepsin C, CELA1, CELA3A and/or structurally related molecules thereto, compositions comprising same and uses thereof in the inhibition and/or prevention of cell and/or tissue necrosis is described. Various applications for the described compounds, and combination therapies are described as well.
Public/Granted literature
- US10968185B2 Substituted thiazoles for preventing and/or treating cell or tissue necrosis Public/Granted day:2021-04-06
Information query
