• 专利标题: Salt of Pyrrolo[2,3-D]pyrimidine Compound and Novel Polymorph of Salt
  • 申请号: US15984900
    申请日: 2018-05-21
  • 公开(公告)号: US20180282342A1
    公开(公告)日: 2018-10-04
  • 发明人: Minhua ChenYanfeng ZhangXiaoyu Zhang
  • 申请人: Crystal Pharmatech Co., Ltd.
  • 优先权: CN201410768119.3 20141212; CN201410789045.1 20141218; CN201510566397.5 20150908
  • 主分类号: C07D487/04
  • IPC分类号: C07D487/04
Salt of Pyrrolo[2,3-D]pyrimidine Compound and Novel Polymorph of Salt
摘要:
The present invention relates to novel crystalline forms of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide(compound I), its salts, and process for preparation thereof. Crystalline forms in the present invention have good stability, low hygroscopicity, good processability, easy treatability and other favorable properties. In addition, the process is simple, low cost, and has an important value for future optimization and development of the drug.
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