Invention Application
- Patent Title: SUBSTITUTED HETEROCYCLIC SULFONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS
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Application No.: US16001770Application Date: 2018-06-06
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Publication No.: US20180282272A1Publication Date: 2018-10-04
- Inventor: Huifen CHEN , Yanyan CHU , Steven DO , Anthony ESTRADA , Baihua HU , Aleksandr KOLESNIKOV , Xingyu LIN , Joseph P. LYSSIKATOS , Daniel SHORE , Vishal VERMA , Lan WANG , Guosheng WU , Po-wai YUEN
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Priority: CNPCT/CN2014/086380 20140912
- Main IPC: C07D207/48
- IPC: C07D207/48 ; C07D451/02 ; C07D491/048 ; C07D401/14 ; C07D405/14 ; C07D403/14 ; C07D403/12 ; C07D417/12 ; C07D401/12

Abstract:
The invention is concerned with the compounds of formula I or II: and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I or II as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
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