- 专利标题： MODIFIED ONCOLYTIC VACCINIA VIRUSES EXPRESSING A CYTOKINE AND A CAR- BOXYLESTERASE AND METHODS OF USE THEREOF
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申请号： US15758689申请日： 2016-09-02
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公开(公告)号： US20180271921A1公开(公告)日： 2018-09-27
- 发明人: Tae Ho HWANG , Nam Hee LEE , Euna CHO
- 申请人： SillaJen, Inc.
- 申请人地址： KR Busan
- 专利权人： SillaJen, Inc.
- 当前专利权人： SillaJen, Inc.
- 当前专利权人地址： KR Busan
- 国际申请： PCT/KR2016/009866 WO 20160902
- 主分类号： A61K35/768
- IPC分类号： A61K35/768 ; C12N9/18 ; C07K14/565 ; A61K38/46 ; A61K38/21 ; A61K45/06 ; A61P35/00
摘要：
The present disclosure pertains to a compositions and combinations for simultaneous, separate or sequential use which comprises (a) an oncolytic vaccinia virus that expresses a cytokine and a carboxylesterase enzyme, and, preferably, (b) a cancer co-drug, and to their uses for the treatment of cancer.
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